AMINOGLYCOSIDES ANTIBIOTICS
TOP 10 MCQ
1. One of the following drug is NOT meant for systemic use [GPAT-2023 SHIFT-II]
(a) Netilmicin
(b) Sisomicin
(c) Neomycin
(d) Paromomycin
2. Which of the following antibiotics produces concentration dependent bactericidal action and also possesses post-antibiotic effect [GPAT-2011]
(a) Ceftazidime
(b) Azithromycin
(c) Amikacin
(d) Piperacillin
3. Amikacin is [GATE-2008]
[P] A semisynthetic aminoglycoside and a derivative of kanamycin
[Q] A semisynthetic aminoglycoside and a derivative of tobramycin
[R] It is administered parenterally and does not cause nephrotoxicity and ototoxicity
[S] It is administered parenterally and is both nephrotoxicity and ototoxicity
(a) [P], [Q]
(b) [P], [R]
(c) [P], [S]
(d) [Q], [S]
4. One of the drugs is excreted primarily by renal tubular secretions. Identify [GATE-1995]
(a) Gentamycin
(b) Kanamycin
(c) Tetracycline
(d) Carbenicillin
5. Streptomycin is a
(a) Peptide
(b) Glycoside
(c) Phospholipid
(d) Glycolipid
6. Mechanism of action of streptomycin
(a) Inhibition of translation
(b) Inhibition of signal transduction
(c) Inhibition of citric acid cycle
(d) Inhibits mitochondria
7. Mechanism of action of Aminoglycosides are
(a) Inhibition of protein synthesis
(b) Damage to cell membrane
(c) Coagulation of proteins
(d) Inhibition of cell wall synthesis
8. Which of the following aminoglycoside is not available for parenteral use
(a) Sisomycin
(b) Amikacin
(c) Framycetin
(d) Gentamycin
9. All of the following drugs are administered orally except
(a) Ciprofloxacin
(b) Cotrimoxazole
(c) Gentamicin
(d) Amoxicillin
10. Widest spectrum aminoglycoside is
(a) Streptomycin
(b) Amikacin
(c) Framycetin
(d) Netilmicin
ANSWER KEY
| 1-c | 2-c | 3-c | 4-a | 5-b | 6-a | 7-a | 8-c | 9-c | 10-b |
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