ANTHELMINTIC DRUGS
TOP 10 MCQ
1. Choose the most appropriate answer [GPAT-2023 SHIFT-II]
[P] Trichuris trichiura – Pig worm
[Q] Strongyloides stercoralis – Thread worm
[R] Taenia solium – Pork worm
[S] Enterobius vermicularis – Chinese worm
(a) Only Q and R are correct
(b) Only P and Q are correct
(c) P, Q, R and S are correct
(d) Only Q, R and S are correct
2. Which of the following attributes are true for describing the mechanism of action of Thiabendazole [GATE-2005]
[P] Neuromuscular blocking causing spastic paralysis
[Q] Blocks the response of the Ascaris muscle to ACh causing flaccid paralysis in the worms
[R] Inhibits the Helminth specific enzyme fumarate reductase
[S] Arrests nematode cell divisions in metaphase by interfering with microtubule assembly
(a) [P], [Q]
(b) [R], [S]
(c) [Q], [S]
(d) [Q], [R]
3. The mechanism of antiparasitic action of Mebendazole and Thiabendazole involves [GATE-2003]
(a) Stimulation of acetylcholine receptors at neuromuscular junctions
(b) Inhibition of dihydrofolate reductase
(c) Interference with microtubule synthesis and assembly
(d) Block thiamine transport
4. The essential structural unit for the anthelmintics activity of mebendazole is [GATE-1990]
(a) Benzoyl group
(b) Benzimidazole
(c) Methyl carbamates
(d) Imidazole
5. Mebendazole is used in all, except
(a) Cysticercosis
(b) Ascariasis
(c) Trichuriasis
(d) Schistosomiasis
6. Albendazole may be used for treatment of all of the following conditions except
(a) Enterobius
(b) Ascariasis
(c) Ancylostoma
(d) Schistosomiasis
7. Drug of choice for cutaneous larva migrans is
(a) Mebendazole
(b) Niridazole
(c) Hetrazan
(d) Thiabendazole
8. Which of the following drugs has both anthelmintic and antiprotozoal activity
(a) Nitazoxanide
(b) Emetine
(c) Chloroquine
(d) Diloxanide furoate
9. Ivermectin is used in the treatment of
(a) Schistosomiasis
(b) Filariasis
(c) Ascariasis
(d) Strongyloidiasis
10. Ivermectin is the drug of choice for which of the following infections
(a) Trichuriasis
(b) Onchocerciasis
(c) Loiasis
(d) Trichinosis
ANSWER KEY
| 1-c | 2-b | 3-c | 4-b | 5-d | 6-d | 7-d | 8-a | 9-d | 10-b |
|
|
|
