ANTIADRENERGIC DRUGS AND DRUGS FOR GLAUCOMA
TOP 10 MCQ
1. A patient with pheochromocytoma is undergoing surgery and has not been administered with alpha receptor blocker. If he is administered with intravenous propranolol, then which of the following effects may be seen [GPAT-2022]
(a) There will be a rise in the blood pressure
(b) There will be a fall in the blood pressure
(c) The blood pressure will not be altered
(d) The patient may suffer severe bronchoconstriction
2. Except one of the following pairs represent drugs used in the treatment of glaucoma and their primary action [GPAT-2020]
(a) Topical prostaglandin analogues: Increase aqueous outflow
(b) Topical beta-adrenergic blockers: Increase aqueous formation
(c) Topical alpha-adrenergic blockers: Decrease aqueous outflow
(d) Topical carbonic anhydrase inhibitors: Decrease aqueous formation
3. Which of the following pair of drugs is considered as selective α1-blockers [GPAT-2019]
(a) Timolol and Metoprolol
(b) Prazosin and Terazosin
(c) Atenolol and Levobunolol
(d) Yohimbine and Corynanthine
4. Which of the following is NOT a cardio selective β-blocker [GPAT-2019]
(a) Bisoprolol
(b) Nebivolol
(c) Acebutolol
(d) Pindolol
5. Topical application of Timolol to the eye would be expected to induce which of the following [GPAT-2017]
(a) Increased formation of aqueous humor
(b) Miosis
(c) Mydriasis
(d) Increased outflow of aqueous humor
6. Characteristics of carvedilol includes [GPAT-2016]
[P] It is a β₁-selective antagonist
[Q] It has both α₁-selective and β-blocking effects
[R] It inhibits vascular smooth muscle mitogenesis
(a) [P] true, [Q] & [R] false
(b) [P], [Q] & [R] true
(c) [Q] true, [P] & [R] false
(d) [P], [Q] & [R] false
7. Which of the following is true for α-blocker, EXCEPT [GPAT-2015]
(a) Blockade of vasoconstriction
(b) Cause nasal stuffiness and miosi
(c) Increased intestinal motility
(d) Tone of smooth muscle in bladder trigone and sphincter is increased
8. Which of the following is selective α₁-selective antagonists [GPAT-2013]
(a) Clonidine
(b) Prazosin
(c) Phentolamine
(d) Yohimbine
9. The drug used during the preoperative preparation for surgical excision of pheochromocytoma is [GPAT-2013]
(a) Atenolol
(b) Phenoxybenzamine
(c) Reserpin
(d) Clonidine
10. Which of the following drugs does NOT induce mydriasis [GPAT-2011]
(a) Atropine
(b) Ephedrine
(c) Phentolamine
(d) Cocaine
ANSWER KEY
| 1-d | 2-b | 3-b | 4-d | 5-d | 6-a | 7-a | 8-b | 9-b | 10-a |
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