ANTITUBERCULAR DRUGS
TOP 10 MCQ
1. A drug which causes pink to brownish skin pigmentation within a week of the initiation of the therapy is [GATE-2003]
(a) Itraconazole
(b) Clofazimine
(c) Lomefloxacin
(d) Neomycin
2. Following combination is suggested in the treatment of Leprosy [GATE-1989]
(a) Dapsone + Ampicillin + Clofazimine
(b) Dapsone + Clofazimine + Rifampin
(c) Dapsone + Erythromycin + Rifampin
(d) Dapsone + Tetracycline + Streptomycin
3. Which of the following is a side effect of Clofazimine
(a) Reddish black skin discoloration
(b) Hemolytic anemia
(c) Flu like syndrome
(d) Axillary freckling
4. Not true about clofazamine
(a) Used in DLE
(b) Causes ichthyosis and hyperpigmentation
(c) Interferes DNA synthesis
(d) Used in lepra reaction
5. Leprosy is also known as
(a) Anthrax
(b) Hansen’s disease
(c) Tyson’s disease
(d) Handen’s disease
6. Leprosy is caused by which microorganism
(a) Clostridium perfringens
(b) Mycobacterium leprae
(c) Mycobacterium tuberculosis
(d) None of the above
7. The drug that should be used for prophylaxis of close contact of a patient suffering from meningococcal meningitis is
(a) Rifampicin
(b) Dapsone
(c) Erythromycin
(d) Amikacin
8. Pigmentation and ichthyosis is side effects of
(a) Clofazamine
(b) Rifampicin
(c) Dapsone
(d) Ethionamide
9. In leprosy, the best bactericidal agent is
(a) Clofazimine
(b) Dapsone
(c) Rifampicin
(d) Ethionamide
10. Most common drug used in leprosy is
(a) Dapsone
(b) Clofazimine
(c) Ethionamide
(d) Ofloxacin
ANSWER KEY
| 1-b | 2-b | 3-a | 4-c | 5-b | 6-b | 7-a | 8-a | 9-c | 10-a |
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