ANTIVIRAL DRUGS
TOP 10 MCQ
1. Which is the nonnucleotide reverse transcriptase inhibitor (NNRTI) [GPAT-2014, 2024]
(a) Lamivudine
(b) Nevirapine
(c) Amantadine
(d) Ribavirin
2. Didanosine can best be described as [GPAT-2014, 2024]
(a) Antiprotozoal
(b) Reverse transcriptase inhibitor
(c) Protease inhibitor
(d) Beta-lactamase inhibitor
3. Which of the following combination is CORRECT [GPAT-2023 SHIFT-II]
(a) Nucleoside reverse transcriptase inhibitors (NRTIs) – Ritonavir
(b) Protease inhibitors – Indinavir
(c) Integrase inhibitors – Saquinavir
(d) Non-nucleoside reverse transcriptase inhibitors (NNRTIs) – Tenofovir
4. Antiretroviral Raltegravir is unique, because of which of its following actions [GPAT 2011, 2015]
(a) Integrase inhibition
(b) CCR5 Co-receptor antagonism
(c) Fusion inhibition
(d) Reverse transcriptase inhibition
5. Which drug is used in the treatment of Hepatitis B?
(a) Lamivudine
(b) Idoxuridine
(c) Zanamivir
(d) Ribavirin
6. HIV may NOT respond to [GPAT-2013]
(a) Nucleoside analogues
(b) Protease inhibitors
(c) Neuraminidase inhibitors
(d) Reverse transcriptase
7. Antiviral action of purine analogues is primarily related to the followings [GPAT-2012]
[P] Inhibition of RNA synthesis
[Q] Inhibition of DNA polymerase
[R] Immuno-modulation
[S] Inhibition of viral penetration
Choose the CORRECT option
(a) R is correct and Q is incorrect
(b) Q is correct and S is incorrect
(c) P is correct and R is incorrect
(d) S is correct and P is incorrect
8. Which of the following is a non-competitive inhibitor of the enzyme reverse transcriptase in HIV [GPAT-2011]
(a) Lamivudine
(b) Nevirapine
(c) Abacavir
(d) Tenofovir
9. Select the correct combination of drugs for the treatment of patients suffering from Hepatitis [GPAT-2010]
(a) Interferon with Ribavirin
(b) Interferon with Zidovudine
(c) Interferon with Stavudine
(d) Interferon with Lamivudine
10. Ganciclovir is mainly used for the treatment of infection caused by [GPAT-2010]
(a) Cytomegalovirus
(b) Candida albicans
(c) Herpes zoster virus
(d) Hepatitis B virus
ANSWER KEY
| 1-b | 2-b | 3-b | 4-a | 5-b | 6-c | 7-b | 8-b | 9-a | 10-a |
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