CNS STIMULANTS AND COGINATION ENHANCER
TOP 10 MCQ
1. Following is an analogue of Amphetamine which produces anorexia without causing stimulation [GPAT-2024]
(a) Fenthuramine
(b) Methylamphetamine
(c) Methylphenidate
(d) Dextroamphetamine
2. Alzheimer’s disease is mainly because of the neurodegeneration of the following part of the brain [GPAT-2023 SHIFT-I]
(a) Hypothalamus
(b) Midbrain
(c) Hippocampus
(d) Cerebellum
3. Characteristic microscopic features observed in Alzheimer’s disease is [GPAT-2019]
(a) Epidural hemorrhagic patches
(b) Depigmentation of substantia nigra
(c) Demyelination of neurons in spinal cord
(d) Presence of neuritic plaques containing a β-amyloid
4. Improvement of memory in Alzheimer’s disease is brought about by drugs which increase transmission in [GPAT-2010]
(a) Cholinergic receptors
(b) Dopaminergic receptors
(c) GABAergic receptors
(d) Adrenergic receptors
5. An NMDA antagonist introduced for treatment of Alzheimer’s disease is [GATE-2009]
(a) Dopamine
(b) Nor-epinephrine
(c) Serotonin
(d) Memantine
6. Strychnine produces convulsions by:
(a) Stimulating NMDA receptors
(b) Facilitating the excitatory transmitter glutamate
(c) Blocking the inhibitory transmitter GABA
(d) Blocking the inhibitory transmitter glycine
7. The drug of choice for hyperkinetic children is
(a) Methylphenidate
(b) Nikethamide
(c) Caffeine
(d) Clonazepam
8. The neurotransmitter system in the brain most affected in Alzheimer’s disease is:
(a) Glutaminergic
(b) GABAergic
(c) Dopaminergic
(d) Cholinergic
9. The following drug claimed to have a therapeutic effect in senile dementia has α-adrenergic blocking activity:
(a) Piracetam
(b) Pyritinol
(c) Codergocrine
(d) Methylphenidate
10. Pyritinol (pyrithioxine) is used as:
(a) Analeptic drug
(b) Cognition enhancing drug
(c) Antiepileptic drug
(d) Antidepressant drug
ANSWER KEY
| 1-a | 2-c | 3-d | 4-a | 5-d | 6-d | 7-a | 8-d | 9-c | 10-b |
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