CORTICOSTEROIDS MCQs Part – 3

CORTICOSTEROIDS

TOP 10 MCQ

1. Glucocorticoids have following effects EXCEPT [GPAT-2019]
(a) Stimulation of immune responses
(b) Resistance to stress
(c) Lipolysis
(d) Protein breakdown and glucose formation

2. Which among the following are the salient features of Glucocorticoids [GPAT-2017]
(a) GCs combine with highly specific cytosolic glucocorticoids
(b) They promote phagocytosis by macrophages
(c) Releases of lytic enzymes
(d) Increases lipid Eicosanoids and prostaglandin genes

3. Corticosteroids are administered to treat some of the given disease states [GPAT-2012]
[P] Peptic ulcer
[Q] Bronchial asthma
[R] Nephrotic syndrome
[S] Myasthenia gravis
Choose the correct statement about use of corticosteroids for the treatment of these diseases
(a) P, Q and S are treated while R is NOT
(b) R, P and S are treated while Q is NOT
(c) Q, R and S are treated while P is NOT
(d) P, Q and R are treated while S is NOT

4. Which of the following steroids shows predominant mineralcorticoid action
(a) Hydrocortisone
(b) Spironolactone
(c) Dexamethasone
(d) Flutocortisone

5. The most potent topical corticosteroid is
(a) Hydrocortisone butyrate cream 0.1%
(b) Betamethasone valerate cream 0.5
(c) Clobetasol propionate cream 0.5%
(d) Clobetasone butyrate cream 0.5%

6. Glucocorticoids act in inflammation by
(a) Lipocortin
(b) IL-2
(c) γ Lipocortin
(d) ↑ CRP

7. Drugs causing Addison’s disease are
(a) Ketoconazole
(b) Cyclosporine
(c) Glucocorticoids
(d) ACTH

8. Glucocorticoids have proved useful in the treatment of
(a) Chemotherapy induced vomiting
(b) Hyperprolactinemia
(c) Parkinson’s disease
(d) Type II diabetes

9. Aldosterone is known to cause sodium retention. Its Na+ retaining action is exerted on which part of the nephron
(a) Proximal convoluted tubule
(b) Ascending limb of loop of Henle
(c) Collecting ducts
(d) Early distal convoluted tubule

10. Steroids are contraindicated in all, EXCEPT
(a) Diabetes mellitus
(b) Hypertension
(c) Eczematous skin disease
(d) Peptic ulcer disease

ANSWER KEY

1-a 2-a 3-c 4-d 5-b 6-c 7-a 8-a 9-c 10-c

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