COUGH AND BRONCHIAL ASTHMA
TOP 10 MCQ
1. Which one of the following drugs that is not absorbed orally, is not a bronchodilator, does not have any direct effects on smooth muscles yet is effective in antigen induced, exercise induced and irritant induced asthma though not all asthmatics respond to it positively [GPAT-2021]
(a) Salbutamol
(b) Montelukast
(c) Sodium cromoglycate
(d) Terbutaline
2. The adverse reaction associated with β2 agonists administered by inhalation or nebulization in the management of asthma does not include [GPAT-2019]
(a) Peripheral vasodilation
(b) Hypertension
(c) Tachycardi
(d) Fine tremor
3. Which of the following describes the effect of Sodium cromoglycate [GPAT-2018]
(a) Mast cell degranulation
(b) Mast cell stabilization
(c) Leukotriene antagonism
(d) Glucocorticoid receptor agonism
4. Many mediators have been implicated in the asthmatic response. The clinical efficacy of pharmacologic intervention with inhibitors or antagonist of the mediators involves following category – EXCEPT [GPAT-2017]
(a) Platelet activating factors
(b) Anticholinergics
(c) Antihistaminics
(d) Cytokine inhibitors
5. PDE-IV enzyme inhibitor agent used in the treatment of asthma [GPAT-2013]
(a) Roflumilast
(b) Amoxicillin
(c) Salbutamol
(d) Montelukast
6. Which of the following drugs can precipitate bronchial asthma [GPAT-2012]
[P] Indomethacin
[Q] Codeine phosphate
[R] Rabeprazol
[S] Theophylline
Choose the correct option
(a) P and R
(b) P and Q
(c) R and S
(d) S and Q
7. Which one of the following anti-asthmatic drugs can cause convulsions and arrhythmia [GPAT-2012]
(a) Prednisolone
(b) Salmeterol
(c) Zafirlukast
(d) Theophylline
8. Zafirlukast acts as [GATE-2005]
(a) β2 adrenoceptor agonist
(b) Cysteinyl-leukotriene receptor antagonist
(c) Muscarinic receptor antagonist
(d) Antihistamine
9. A prodrug of Terbutaline is [GATE-2005]
(a) Zafirlukast
(b) Salmeterol
(c) Bambuterol
(d) Nedocromil sodium
10. Warfarin interacts with this anti-asthmatic drug and increases prothrombin time [GATE-2005]
(a) Budesonide
(b) Zafirlukast
(c) Salmeterol
(d) Bambuterol
ANSWER KEY
| 1-c | 2-b | 3-b | 4-c | 5-a | 6-b | 7-d | 8-b | 9-c | 10-b |
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