DRUG AFFECTING COAGULATION AND THROMBOSIS
TOP 10 MCQ
1. Which of the following drugs possesses antiplatelet effects [GPAT-2019]
(a) Erythropoietin
(b) Urokinase
(c) Desmopressin
(d) Clopidogrel
2. Which of the following directly inhibits Factor Xa [GPAT-2019]
(a) Dabigatran
(b) Warfarin
(c) Bivalirudin
(d) Rivaroxaban
3. Which of the following inactive clotting factor is activated by the vitamin-K as coenzyme [GPAT-2019]
(a) I, II, III, IV
(b) II, V, IX, X
(c) II, V, VI, VIII
(d) II, VII, IX, X
4. Hemophilia A is a disease characterized by deficiency of [GPAT-2018]
(a) Factor VIII
(b) Factor II
(c) Factor VII
(d) Factor V
5. Identify the clotting factor which is known as Stuart factor or thrombokinase [GPAT-2018]
(a) Clotting factor – IV
(b) Clotting factor – VIII
(c) Clotting factor – X
(d) Clotting factor – XII
6. Pernicious anemia is a form of which class of anemia [GPAT-2016]
(a) Microcytic normochromic
(b) Microcytic hypochromic
(c) Macrocytic megaloblastic
(d) Macrocytic nonmegaloblastic
7. Which of the following is inhibiting Adenosine deaminase [GPAT-2016]
(a) Clopidogrel
(b) Dipyridamole
(c) Ticlopidine
(d) Abciximab
8. Tranexamic acid act as [GPAT-2015]
(a) Haematinics
(b) Anticoagulant
(c) Plasminogen inhibitor
(d) Plasminogen activator
9. Drug combination warfarin/vitamin K results is a specific interaction-identify [GPAT-2014, GATE-2001]
(a) Antagonistic
(b) Increased sedation
(c) No known interaction
(d) Harmful only in the presence of oxidizing agents
10. Which of the following mechanism is NOT related to platelet aggregation inhibitory action [GPAT-2011]
(a) ADP receptor antagonism
(b) Glycoprotein IIb/IIIa receptor
(c) Phosphodiesterase inhibition
(d) Prostacyclin inhibition
ANSWER KEY
| 1-d | 2-d | 3-d | 4-a | 5-c | 6-c | 7-b | 8-c | 9-a | 10-d |
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