HYPOLIPIDEMIC DRUGS
TOP 10 MCQ
1. The quadruple therapy of Helicobacter pylori infection includes [GPAT-2022]
(a) Bismuth subsalicylate, Metronidazole, Tetracycline and a proton pump inhibitor
(b) Streptomycin, Metronidazole, Tetracycline and a proton pump inhibitor
(c) Sulfasalazine, Metronidazole, Tetracycline and a proton pump inhibitor
(d) Bismuth subsalicylate, Metronidazole, Azithromycin and a proton pump inhibitor
2. Select the ulcer protective drug from the following [GPAT-2019]
(a) Oxyphenonium
(b) Metronidazole
(c) Misoprostol
(d) Sucralfate
3. Which one of the following is systemic antacid [GPAT-2015]
(a) Magnesium hydroxide
(b) Sodium citrate
(c) Sucralfate
(d) Carbenoxolone
4. Magnesium trisilicate is considered to be a better antacid than aluminium hydroxide due to its following additional properties [GPAT-2011]
[P] It has a fixed chemical composition
[Q] It forms colloidal silicon dioxide
[R] Magnesium ions overcome constipation
[S] Magnesium ions cause higher inhibition of pepsin than aluminium ions
Choose the correct combination of statements
(a) Q & S
(b) R & S
(c) P & Q
(d) Q & R
5. From the structural features of the drugs, predict which will be ionized in the stomach [GATE-2004]
(a) Famotidine
(b) Enalapril
(c) Tolbutamide
(d) Enalapril and Tolbutamide
6. Famotidine acts as [GATE-2004]
(a) H₁ histamine antagonist
(b) H₂ histamine antagonist
(c) Proton pump inhibitor
(d) H₂ histamine agonist
7. An organism which has been implicated as a possible cause of chronic gastritis and peptic ulcer is [GATE-2003]
(a) Campylobacter jejuni
(b) Escherichia coli
(c) Helicobacter pylori
(d) Giardia lamblia
8. Which histamine H₂ blocker has most marked inhibitory effect on microsomal cytochrome P450 enzyme
(a) Cimetidine
(b) Ranitidine
(c) Roxatidine
(d) Famotidine
9. Choose the drug which blocks basal as well as stimulated gastric acid secretion without affecting cholinergic, histaminergic or gastrin receptors
(a) Famotidine
(b) Loxatidine
(c) Omeprazole
(d) Pirenzepine
10. The drug beneficial in NSAID induced gastric ulcer
(a) PGE₁ agonist
(b) PGE₂ agonist
(c) PGD₂ agonist
(d) PGF₂α agonist
ANSWER KEY
| 1-a | 2-d | 3-b | 4-d | 5-a | 6-b | 7-c | 8-a | 9-c | 10-a |
|
|
|
