ESTROGEN, PROGESTRONE AND CONTRACEPTIVE
TOP 10 MCQ
1. Which of the following has been found to act as a male contraceptive without affecting libido and potency [GPAT-2023 SHIFT-I]
(a) Cyproterone
(b) Gossypol
(c) Centchroman
(d) Gosrelin
2. All of the following statements regarding estrogen therapy in postmenopausal women are true EXCEPT [GPAT-2017]
(a) It restores the loss of bone mass due to osteoporosis
(b) It may be useful to treat vasomotor symptoms
(c) Administration in a regimen including a progestin
(d) It is useful in the treatment of atrophic vaginitis
3. _______ is the emergency contraceptive [GPAT-2013]
(a) Levonorgestrel
(b) Misoprostol
(c) Norethindrone
(d) Estradiol
4. Which one of the followings is the most likely positive sign of pregnancy when detected in urine [GPAT-2012]
(a) Estrogens
(b) Progesteron
(c) Human Chorionic Gonadotropin (HCG)
(d) Corticotropic Hormone
5. Most of the emergency contraceptives have which one of the following active ingredients [GATE-2011]
(a) Estradiol
(b) Norethindrone
(c) Misoprostol
(d) Levonorgestrel
6. Mifepristone and gemeprost combination is used for medical termination of pregnancy. The action is caused due to which of the following mechanisms [GATE-2011]
(a) Mifepristone is an antiestrogen while gemeprost is a prostaglandin E receptor agonist
(b) Mifepristone is an antiprogestin while gemeprost is a prostaglandin E receptor agonist
(c) Mifepristone is an antiandrogen while gemeprost is a prostaglandin E receptor agonist
(d) Mifepristone is an antiprogestin while gemeprost is a prostaglandin E receptor antagonist
7. Gossypol, a compound which has received major attention as a male contraceptive [GATE-2006]
[P] Is a hydroxylated binaphthalene derivative found in cotton seed oil
[Q] Is an oryzanol ester, found in rice bran oil
[R] Exhibits toxicity such as hypokalemic induced paralysis
[S] Acts as an androgen antagonist
Identify the CORRECT statements
(a) [Q], [R]
(b) [P], [S]
(c) [Q], [S]
(d) [P], [R]
8. One of the drugs is odd one in terms of its biological action [GATE-2002]
(a) Diethyl Stilbesterol
(b) Tamoxifen
(c) Ethinyl Estradiol
(d) Mestranol
9. The gonadal hormones like Estrogens, Androgens and Progestins binds with [GATE-1998]
(a) Receptors located in the cytoplasm
(b) Receptors located in the nucleus of the cell
(c) Receptors located in the contractile vacuoles
(d) None of these
10. Estrogenic and Progestogenic combination mainly [GATE-1989]
(a) Inhibits the ovulation
(b) Inhibits the implantation of the fertilized ovum
(c) Inhibits the fertilization of ovum
(d) Inhibits development of endometrium
ANSWER KEY
| 1-b | 2-a | 3-a | 4-c | 5-d | 6-b | 7-b | 8-b | 9-a | 10-a |
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