TOP 10 MCQ
1. In Gilles de la Tourette’s syndrome which drug is used [GPAT-2024]
(a) Halothane
(b) Haloperidol
(c) Sulpiride
(d) Clozapine
2. Two pore domain K⁺ ions channels are opened by which one of the following categories of anaesthetic [GPAT-2020]
(a) Barbiturates
(b) Benzodiazepines
(c) Opioid analgesics
(d) Halogenated inhalation anaesthetic
3. Accepted measure of anaesthetic potency [GPAT-2015]
(a) Lipid solubility
(b) Speed of induction
(c) Presence of a “second gas effect”
(d) Minimum alveolar concentration (MAC value)
4. GABA, an important transmitter in the brain [GATE-2006]
[P] Is an inhibitory transmitter
[Q] Is an excitatory transmitter
[R] Increases chloride conductance
[S] Is antagonized by Naloxone
Identify the correct statements
(a) [P], [Q]
(b) [Q], [R]
(c) [P], [R]
(d) [R], [S]
5. Which general anaesthetic selectively inhibits excitatory NMDA receptors
(a) Thiopentone
(b) Halothane
(c) Desflurane
(d) Ketamine
6. The minimal alveolar concentration of an inhalational anaesthetic is a measure of its
(a) Potency
(b) Therapeutic index
(c) Diffusibility
(d) Oil water partition coefficient
7. General anaesthetics produce immobility in response to painful surgical stimuli by acting primarily at the
(a) Motor cortex
(b) Basal ganglia
(c) Thalamus
(d) Spinal cord
8. Which of the following is a sign of deep anaesthesia
(a) Appearance of tears in eyes
(b) Resistance to passive inflation of lungs
(c) Fall in blood pressure
(d) Patient makes swallowing movements
9. Select the inhalational general anaesthetic which is metabolized in the body to a significant extent
(a) Sevoflurane
(b) Isoflurane
(c) Ether
(d) Halothane
10. The minimal alveolar concentration (MAC) of halothane is
(a) 75%
(b) 25%
(c) 7.5
(d) 0.75%
ANSWER KEY
| 1-b | 2-d | 3-d | 4-c | 5-d | 6-a | 7-d | 8-c | 9-d | 10-d |



