GENERAL CONSIDERATION
TOP 10 MCQ
1. Following pairs represent antibiotic and its source. Identify the CORRECT pair [GPAT-2020]
(a) Griseofulvin : Bacteria
(b) Polyenes : Fungi
(c) Colistin : Fungi
(d) Macrolides : Actinomycetes
2. Which of the following is NOT a desirable characteristic for an effective urinary tract antimicrobial drug [GPAT-2016]
(a) High activity against negative bacilli
(b) High volume of distribution in body
(c) Low level of protein binding
(d) Shows short biological half life
3. Colistin is obtained from [GPAT-2016]
(a) Bacteria
(b) Fungi
(c) Actinomycetes
(d) Herbs
4. The antibiotics and their adverse effect are mentioned below [GATE-1991]
Antibiotic                              Adverse effect
Chloramphenicol                     [P] Hemolytic anemia
Erythromycin                        [Q] Hepatotoxicity
Cephalosporins                      [R] CNS toxicity
Streptomycin                        [S] Nephrotoxicity
                                     [T] Ototoxicity
(a) 1-[T], 2-[Q], 3-[R], 4-[S]
(b) 1-[P], 2-[Q], 3-[S], 4-[T]
(c) 1-[P], 2-[Q], 3-[T], 4-[S]
(d) 1-[P], 2-[T], 3-[R], 4-[S]
5. The undesirable effects of the antibiotics are listed in [P] to [T] match them [GATE-1990]
Antibiotic                                        Side effect
Tetracycline                                    [P] Gray-baby syndrome
Streptomycin                                   [Q] Discoloration of teeth
Chloramphenicol                               [R] Jaundice
Rifampicin                                     [S] Obesity
                                               [T] Ototoxicity
(a) 1-[Q], 2-[T], 3-[P], 4-[R]
(b) 1-[P], 2-[Q], 3-[R], 4-[S]
(c) 1-[T], 2-[Q], 3-[R], 4-[P]
(d) 1-[R], 2-[T], 3-[Q], 4-[S]
6. Colistin is obtained from
(a) Bacteria
(b) Fungi
(c) Actinomycetes
(d) Herbs
7. All act by inhibiting cell wall synthesis except
(a) Aminoglycoside
(b) Penicillin
(c) Cycloserine
(d) Bacitracin
8. All of the following drugs act on cell membrane except
(a) Nystatin
(b) Griseofulvin
(c) Amphotericin B
(d) Polymyxin B
9. Antibiotic not inhibiting protein synthesis
(a) Streptogramins
(b) Aminoglycosides
(c) Bacitracin
(d) Linezolide
10. Antibiotics acting by inhibition of protein synthesis include
(a) Penicillin
(b) Vancomycin
(c) Aminoglycoside
(d) Fluoroquinolones
ANSWER KEY
| 1-d | 2-b | 3-a | 4-d | 5-a | 6-a | 7-a | 8-b | 9-c | 10-c |
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