HAEMATINICS AND ERYTHROPOIETIN
TOP 10 MCQ
1. Most common type of megaloblastic anemia caused by malabsorption of vitamin B12 and characterized by decreased production of hydrochloric acid in the stomach and a deficiency of intrinsic factor is [GPAT-2023 SHIFT-II]
(a) Iron deficiency anemia
(b) Sideroblastic anemia
(c) Pernicious anemia
(d) Aplastic anemia
2. Macrocytic anemia is noted with all of the following except:
(a) Phenytoin
(b) Methotrexate
(c) Pyrimethamine
(d) Ciprofloxacin
3. An iron compound used as haematinic agent must meet two requirements i.e. it should be biologically available and be non-irritating. Which one of the following compounds meet the above two requirements most closely [GPAT-2011]
(a) Ferric chloride
(b) Ferric ammonium sulphate
(c) Ferric ammonium citrate
(d) Ferrous thioglycolate
4. An example of hemopoietic growth factor is [GATE-2004]
(a) Platelet derived growth factor
(b) Epidermal growth factor
(c) Iron dextran
(d) Erythropoietin
5. Methyl malonyl CoA mutase which catalyzes the conversion of propionyl CoA to succinyl utilizes the prosthetic group derived from [GATE-2002]
(a) Cyanocobalamine
(b) Pyridoxine
(c) Thiamine
(d) Nicotinamide
6. For oral iron supplements used for iron deficiency anemia
(a) Tolerable dose will deliver 40 to 60 mg of iron per day
(b) Mass of total salt is important in determining daily dose
(c) Treatment should be stopped as soon as normal hemoglobin level is reached
(d) Desired rate of hemoglobin improvement is 0.5 mg per day
7. Filgrastim is used for the treatment of
(a) Neutropenia
(b) Anaemia
(c) Polycythaemia
(d) Neutrophilia
8. The most appropriate drug used for chelation therapy in beta thalassemia major is
(a) Oral desferrioxamine
(b) Oral deferiprone
(c) Intramuscular EDTA
(d) Oral succimer
9. Iron is most commonly absorbed from
(a) Duodenum and upper jejunum
(b) Lower jejunum
(c) Stomach
(d) Ileum
10. Megaloblastic anaemia may be caused by all of the following, except
(a) Dilantin toxicity
(b) Vitamin B12 deficiency
(c) Folic acid deficiency
(d) Long term aspirin intake
ANSWER KEY
| 1-c | 2-b | 3-c | 4-d | 5-a | 6-a | 7-a | 8-b | 9-a | 10-d |
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