HORMONE AND DRUGS AFFECTING CALCIUM BALANCE
TOP 10 MCQ
1. Which is NOT true about Calcitriol [GPAT-2019]
(a) It is active form of Vitamin D
(b) It enhances reabsorption of calcium and phosphate from bone
(c) It prevents tubular reabsorption of calcium and phosphate
(d) Enhances absorption of calcium and phosphate from intestine
2. The CORRECT statement about Vitamin D is [GPAT-2018]
(a) The oral administration of 1,25-dihydroxycholecalciferol is required in chronic renal failure
(b) 25-Hydroxycholecalciferol is the active form of the vitamin
(c) Vitamin D antagonizes the effects of parathyroid hormone
(d) A deficiency of vitamin D causes an increase in calcitonin secretion
3. A peptide hormone which inhibits bone resorption and given as nasal spray is [GATE-2009]
(a) Cortisol
(b) Alendronate
(c) Calcitonin
(d) Calcitriol
4. All of the following decrease bone resorption in osteoporosis except
(a) Alendronate
(b) Etidronate
(c) Strontium
(d) Teriparatide
5. Which of the following drug is a SERM useful for treatment of osteoporosis
(a) Raloxifene
(b) Bisphosphonate
(c) Strontium
(d) Estradiol
6. Both decreased bone resorption and increased bone formation is caused by
(a) Strontium ranelate
(b) Ibandronate
(c) Teriparatide
(d) Calcitonin
7. Bisphosphonates act by
(a) Increasing the osteoid formation
(b) Increasing the mineralization of osteoid
(c) Decreasing the osteoclast mediated resorption of bone
(d) Decreasing the parathyroid hormone secretion
8. Bone resorption is enhanced by
(a) PGDâ‚‚
(b) PGFâ‚‚
(c) PGEâ‚‚
(d) PGIâ‚‚
9. Clinical effect of vitamin D is reduced by
(a) Simultaneous ingestion of phytates
(b) Simultaneous ingestion of lactose
(c) Acidic environment
(d) None of the above
10. Normal range of plasma calcium is
(a) 1-2 mg
(b) 9-11 mg
(c) 20-25 mg
(d) 80-100 mg
ANSWER KEY
| 1-c | 2-a | 3-c | 4-d | 5-a | 6-a | 7-c | 8-c | 9-a | 10-b |
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