LOCAL ANAESTHETICS
TOP 10 MCQ
1. What is the primary mechanism of action of local anesthetics [GPAT-2012]
(a) Activation of ligand-gated potassium channels
(b) Blockade of voltage-gated sodium channels
(c) Stimulation of voltage-gated N-type calcium channels
(d) Blockade of GABA-gated chloride channels
2. Which of the following is used as a local anesthetic in the formulation of parenteral products [GATE-2006]
(a) Acetic acid
(b) Benzyl alcohol
(c) Ethyl alcohol
(d) Sorbitol
3. Maximum dose of lignocaine given with adrenaline for infiltration anaesthesia is
(a) 3 mg/kg
(b) 5 mg/kg
(c) 7 mg/kg
(d) 10 mg/kg
4. Anaesthetic agent with vasoconstrictor is contraindicated in
(a) Digital block
(b) Spinal block
(c) Epidural block
(d) Regional anaesthesia
5. Methemoglobinemia is caused by
(a) Prilocaine
(b) Ropivacaine
(c) Bupivacaine
(d) Procaine
6. First local anaesthetic used in clinical anaesthesia was
(a) Bupivacaine
(b) Procaine
(c) Lidocaine
(d) Cocaine
7. From which of the following routes, absorption of local anaesthetic is maximum
(a) Intercostal
(b) Epidural
(c) Brachial
(d) Caudal
8. In spinal anaesthesia the drug is deposited between
(a) Dura and arachnoid
(b) Pia and arachnoid
(c) Dura and vertebra
(d) Into the cord substance
9. Bupivacaine poisoning is treated with all except
(a) Esmolol
(b) Sotalol
(c) Lignocaine
(d) Diazepam
10. The local anaesthetic with the longest duration of action is
(a) Procaine
(b) Chloroprocaine
(c) Lignocaine
(d) Dibucaine
ANSWER KEY
| 1-b | 2-b | 3-c | 4-a | 5-a | 6-d | 7-a | 8-b | 9-c | 10-d |
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