NIPER 2020
1. Which of the following is a cytokine inhibitor used as anti-inflammatory?
(a) Nimesulide
(b) Abatacept.
(c) Diclofenac
(d) Nabumetone
2. Remdesivir interferes with the action of which viral enzyme?
(a) RNA-dependent RNA polymerase
(b) Exoribonuclease
(c) DNA-dependent RNA polymerase
(d) DNA gyrase
3. Capitsol is an excipient based on:
(a) PLA polymer
(b) PLGA polymer
(c) Cyclodextrin
(d) PEG
4. 6-Fluoro-3-oxo-3,4-dihydro-2-pyrazine carboxamide is the IUPAC name of which drug?
(a) Ritonavir
(b) Favipiravir
(c) Remdesivir
(d) Pyrazinamide
5. This reaction mechanism is favored by 3° substrates, low temperatures, polar solvents, and low concentrations of very weak bases.
(a) E1
(b) E2
(c) SN1
(d) SN2
6. Who is the recipient of “World Entrepreneur of The Year Award” for 2020?
(a) Vivekchand Sehgal
(b) Siddharth Lal
(c) Kiran Mazumdar-Shaw
(d) Rahul Bajaj
7. In one of the following sulfonamides, pyrimidine ring is absent. Which is it?
(a) Sulfisomidine
(b) Sulfadimidine
(c) Sulfadoxine
(d) Sulfisoxazole
8. Histamine structure is represented by:
(a) 3,4-Dihydroxyphenethylamine
(b) 2-(1H-Imidazol-5-yl)ethanamine
(c) 2-(1H-Imidazol-4-yl)ethanamine
(d) 2-Amino-3-(1H-imidazol-4-yl) propanoic acid
9. P2Y12 is a chemoreceptor for adenosine diphosphate (ADP) that:
(a) Mediates platelet aggregation
(b) Mediates WBC stimulation
(c) Binds to clopidogrel reversibly
(d) Mediates fibrinolysis
10. Neopentane and 2-methyl butane are which type of isomers?
(a) Positional isomers
(b) Chain isomers
(c) Isomers
(d) Diastereoisomers
ANSWER KEY
| 1-b | 2-a | 3-c | 4-b | 5-d | 6-c | 7-d | 8-c | 9-a | 10-b |
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