NIPER 2023
1. Cannizzaro reaction gives which of the following products?
(a) Ketone and aldehyde
(b) Acid and alcohol
(c) Alcohol and ester
(d) Acid and amide
2. The Rh in blood groups are decided by reaction with which antibodies:
(a) Anti-A
(b) Anti-B
(c) Anti-D
(d) Anti-H
3. What is not true about Neprilysin inhibitor?
(a) Sacubitril is neprilysin inhibitor
(b) It blocks the breakdown of natriuretic peptides, angiotensin I and bradykinin
(c) Omapatrilat is pure neprilysin inhibitor
(d) Neprilysin inhibitors can be used with AT₁ receptor antagonist
4. Which one of the following guidelines is followed for analytical method validation, if the method of analysis is not official in any pharmacopoeia or appears in other recognized references?
(a) ICH
(b) WHO
(c) GLP
(d) HACCP
5. What is the long form of DSMB?
(a) Direct Server Message Block
(b) Data Safety Monitoring Board
(c) Diagnostic and Statistical Manual Board
(d) DigitalShow Multimedia Broadcasting
6. The volume of distribution equals ____ divided by initial drug concentration:
(a) Clearance
(b) Half-life
(c) Initial drug concentration
(d) Dose
7. Two daughter cells are formed in mammals by:
(a) Mitosis
(b) Meiosis
(c) Cytokinesis
(d) Binary fusion
8. Fluorine is:
(a) H bond donor
(b) H bond acceptor
(c) Either donor or acceptor based on the atom to which it is attached
(d) Neither donor nor acceptor due to anomalous behavior
9. Numbers of nitrogens in capreomycin are:
(a) 10
(b) 12
(c) 14
(d) 16
10. When the velocity of enzyme activity is plotted against substrate concentration, which of the following is obtained?
(a) Rectangular hyperbolic curve
(b) Straight line with positive slope
(c) Sigmoidal curve
(d) Parabolic curve
ANSWER KEY
| 1-b | 2-c | 3-c | 4-a | 5-b | 6-d | 7-a | 8-b | 9-c | 10-a |
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