PHARMACEUTICAL AERASOL
TOP 10 MCQ
1. Which of the following is the common chemical name for Propellant 11 [GPAT – 2023 SHIFT – I]
(a) Trichloromonofluoromethane
(b) Dichlorodifluoromethane
(c) Dichlorotetrafluoroethane
(d) Chloropentafluoroethane
2. The law of relative lowering of vapour pressure was given by [GPAT – 2023 SHIFT – I]
(a) Raoult
(b) Ostwald
(c) Henry
(d) Van’t Hoff
388. Match List I with List II [GPAT – 2023 SHIFT – II]
LIST–I (Part of the Valve Assembly)                  LIST–II (Purpose of Parts)
1. Gasket                                [P] Links the dip tube and the stem and the actuator
2. Spring                                [Q] Prevents the leakage
3. Mounting cup                          [R] Holds the gasket in place
4. Housing                               [S] Holds the valve in place
Choose the correct answer from the options given below:
(a) 1-[R], 2-[Q], 3-[S], 4-[P]
(b) 1-[Q], 2-[R], 3-[S], 4-[P]
(c) 1-[S], 2-[P], 3-[Q], 4-[R]
(d) 1-[R], 2-[P], 3-[S], 4-[Q]
389. Given below are two statements, one is labelled as Assertion [A] and the other is labelled as Reason [R] [GPAT – 2022]
Assertion [A]: The pressure filling method for filling pharmaceutical aerosol is usually preferred over cold filling method.
Reason [R]: Because with pressure filling method high production speed can be achieved and less propellant is lost.
In light of the above statements, choose the correct answer from the options given below:
(a) Both [A] and [R] are true and [R] is the correct explanation of [A]
(b) Both [A] and [R] are true but [R] is NOT the correct explanation of [A]
(c) [A] is true but [R] is false
(d) [A] is false but [R] is true
390. In case of aerosol testing valve delivering acceptance criteria for a volume of 54 ml [GPAT – 2019]
(a) ±75%
(b) ±5
(c) ±10%
(d) ±15%
391. Which of the following is a propellant number of dichlorotetrafluoroethane [GPAT – 2016]
(a) 114
(b) 014
(c) 124
(d) 012
392. Which particle size of drug will get deposited in the alveoli [GPAT – 2013]
(a) >20 µm
(b) <0.6 µm
(c) 2 and 6 µm
(d) 1–2 µm
393. Heckel’s plot represents [GPAT – 2013]
(a) Extent of plastic and elastic deformation of material during compaction
(b) Force–time of force–displacement relationship
(c) Pressure–porosity (volume) relationship
(d) Stress relaxation measurements
394. Containers used for aerosols should withstand a pressure of [GPAT – 2012]
(a) 130–150 psig at 130°F
(b) 140–180 psig at 130°F
(c) 140–170 psig at 120°F
(d) 120–140 psig at 120°F
395. Department of Transport Test (DOT) is performed for which of the following [GPAT – 2011]
(a) Strip packing
(b) Aerosols
(c) Injection packing
(d) Glass containers
ANSWER KEY
| 1-a | 2-a | 3-b | 4-a | 5-d | 6-a | 7-d | 8-c | 9-b | 10-b |
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