PHARMACEUTICAL CALCULATION GPAT MCQs Part – 3

TOP 10 MCQ

1. Find the concentration of sodium chloride required to make a 1 per cent solution of boric acid, iso-osmotic with blood plasma. (Given: The freezing-point of 1% w/v solution of boric acid is 0.288°C. The freezing-point of 1% w/v solution of sodium chloride is −0.576°C)
(a) 0.405% w/v
(b) 0.402% w/v
(c) 0.409% w/v
(d) 0.503% w/v

2. What is the percentage of alcohol in a mixture obtained by mixing 5 L of 25%, 3 L of 40% and 2 L of 15% alcohol [GPAT-2023 SHIFT-I]
(a) 27.5% v/v
(b) 30.5% v/v
(c) 25.5% v/v
(d) 26.5% v/v

3. A 2.0% saline solution is [GPAT-2023 SHIFT-II]
(a) Hypotonic
(b) Hypertonic
(c) Isotonic
(d) Iso-osmotic

4. What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800 mL of 65% v/v alcohol [GPAT-2016, GPAT-2014, GPAT-2018]
(a) 480 mL of 95% and 320 mL of 45% alcohol
(b) 320 mL of 95% and 480 mL of 45% alcohol
(c) 440 mL of 95% and 360 mL of 45% alcohol
(d) 360 mL of 95% and 440 mL of 45% alcohol

5. The proportion of NaCl liquid to give 1.5% solution of drug isotonic with blood plasma is (The freezing point of 1% w/v solution of drug is −0.122 and NaCl is −0.576°C) [GPAT-2018]
(a) 0.79%
(b) 0.585%
(c) 0.9%
(d) 0.5%

6. In Bismuth subgallate suppositories B.P.C, when no strength of the drug is specified, B.P.C directs bismuth subgallate per suppository [GPAT-2017]
(a) 300 mg
(b) 200 mg
(c) 100 mg
(d) 400 mg

7. 0.1 gms contains [GPAT-2016]
(a) 1000 mg
(b) 100 mg
(c) 10 mg
(d) 1 mg

8. How much of 90% and 20% alcohols are required to produce 350 ml of 60% alcohol [GPAT-2015]
(a) 250 ml, 100 ml
(b) 300 ml, 50 ml
(c) 200 ml, 150 ml
(d) 150 ml, 200 ml

9. How much quantity (in grams) of sodium chloride is needed to make 30 ml of a 2% isotonic drug (sodium chloride equivalent 0.20) solution [GPAT-2012]
(a) 0.60
(b) 0.27
(c) 0.15
(d) 0.12

10. How many ml of 50% (w/v) dextrose solution and how many ml of 5% (w/v) dextrose solution are required to prepare 4500 ml of a 10 (w/v) solution [GPAT-2011]
(a) 500 ml of 50% and 4000 ml of 5%
(b) 1000 ml of 50% and 3500 ml of 5%
(c) 4000 ml of 50% and 500 ml of 5%
(d) 1500 ml of 50% and 3000 ml of 5%

ANSWER KEY