PHARMACOKINETICS DRUGS INTERACTION
TOP 10 MCQ
1. The toxicity of quinidine is increased, when antacids are co-administered on account of
(a) Decreased metabolism in liver
(b) Increased absorption in gastrointestinal tract
(c) Increased re-absorption in renal tubule
(d) Reduced protein binding in blood
2. Medication for gastrointestinal motility include all of the
(a) Erythromycin
(b) Reglan
(c) Phenytoin
(d) Cisapride
3. To avoid gastric upset, iron supplements should be taken
(a) Between meals
(b) In very small doses
(c) With large amounts of water
(d) With meal
4. A client is taking the anticoagulant warfarin. The health client’s intake of
(a) Folate
(b) Vitamin K, herbs, and dietary supplements
(c) Vitamin D, caffeine, oxalates, and phytates
(d) Calcium, vitamin D, caffeine, and licorice
5. Penicillin with probenecid causes
(a) Elevated plasma level of Penicillin
(b) Elevated plasma level of Probenecid
(c) Decreased plasma level of Probenecid
(d) Decreased plasma level of Penicillin
6. Aspirin with metoclopramide causes
(a) Increased rate of absorption of Aspirin
(b) Increased rate of absorption of Metoclopramide
(c) Decreased rate of absorption of Metoclopramide
(d) Decreased rate of absorption of Aspirin
7. When Sulphonamides and antacids are given together, enhanced dissolution and absorption rate of Sulphonamides. It is example of
(a) Metabolism interaction
(b) Distribution interaction
(c) Absorption interactio
(d) Excretion interaction
8. When Lithium bicarbonate is given with NSAIDs
(a) Decreased renal clearance of lithium
(b) Increased renal clearance of lithium
(c) Increased renal clearance of NSAIDs
(d) Decreased renal clearance of NSAIDs
9. The formation of an insoluble precipitate as a result of mixing calcium and phosphate is an example of one of the following interaction
(a) Chemical
(b) Medicinal
(c) Physical
(d) Therapeutic
10. Object drug is decided based on one of the following behaviour
(a) Does not change its own behaviour
(b) Narrow therapeutic range
(c) Protein bound
(d) Wide therapeutic range
ANSWER KEY
| 1-c | 2-c | 3-d | 4-b | 5-a | 6-a | 7-c | 8-a | 9-a | 10-b |
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