PITUITARY, THYROID HORMONES AND THYROID AND THYROID INHIBITORS
TOP 10 MCQ
1. Name the gland that is located at the base of the throat, just inferior to the laryngeal prominence (Adam’s apple) [GPAT-2024]
(a) Pituitary
(b) Pineal gland
(c) Hypothalamus
(d) Thyroid
2. Prominent biochemical features of Graves’ disease are [GPAT-2023 SHIFT-1]
(a) Decreased ionized calcium in body fluids
(b) Decreased T3 and T4 in circulation
(c) Increased ionized calcium in body fluids
(d) Increased T3 and T4 in circulation
3. Conversion of T4 to T3 inhibition is associated with [GPAT-2021]
(a) Propylthiouracil
(b) Radioactive iodine
(c) Lugol’s iodine
(d) Carbimazole
4. Which one of the following is a organ specific localized autoimmune disease [GPAT-2020]
(a) Grave’s disease
(b) Scleroderma
(c) Polyarteritis nodosa
(d) Rheumatoid arthritis
5. Identify the hormone that stimulates sperm production in testes and ovulation in females [GPAT-2018]
(a) Prolactin
(b) Luteinizing hormone
(c) Follicle stimulating hormone
(d) Adrenocorticotropic hormone
6. The thymus secretes several hormones related to the immunity. These hormones promote the maturation of T- lymphocyte cells. These hormones are [GPAT-2017]
1. Thymosin
2. Thymic humoral factor
3. Thymic factor
4. Interleukins
(a) Only 1, 2
(b) 1, 2 and 3
(c) Only 3
(d) Only 4
7. Insulin and Thyroxine arrive at an organ / tissue / cell at the same time. Thyroxine causes an effect on the organ but insulin does NOT because [GPAT-2017]
(a) The organ cell have receptors for thyroxine but no receptor for insulin
(b) Thyroxine is a lipid-soluble hormone and insulin is water soluble
(c) The target cell in the organ have up-regulated for thyroxine
(d) Thyroxine is local hormone and insulin is a circulating hormone
8. Indicate which one of the following drugs may interfere with the uptake of I-131 in thyroid gland [GPAT-2016]
(a) Beta-blockers
(b) Alpha-blockers
(c) Calcium channel blockers
(d) Amiodarone
9. Wolff-chaikoff effect is [GPAT-2013]
(a) Reduced Thyroxine synthesis by radiotherapy
(b) Reduced Thyroxine synthesis by Propylthiouracil
(c) Reduced Thyroxine synthesis by Iodides
(d) None of these
10. A 48 years old woman is having the symptoms of weight gain, cold intolerance, constipation, bradycardia, puffy face, lethargy and dry skin. These symptoms are suggestive of which of the followings [GPAT-2012]
(a) Over use of corticosteroid
(b) Hypothyroidism
(c) Estrogen deficiency
(d) Over use of thyroxin sodium
ANSWER KEY
| 1-d | 2-d | 3-a | 4-a | 5-c | 6-b | 7-a | 8-d | 9-c | 10-b |
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