SKELETAL MUSCLE RELAXANTS
TOP 10 MCQ
1. D-Tubocurarine produces skeletal muscle relaxation by inhibiting [GPAT-2020]
(a) Ganglionic nicotinic receptors
(b) Muscarinic receptors
(c) Nicotinic receptors in neuromuscular junction
(d) Alpha-adrenergic receptors
2. All of the given four drugs are neuromuscular blocking agents [GPAT-2012]
[P] Gallamine
[Q] Succinylcholine
[R] Vecuronium
[S] d-Tubocurarine
Choose the correct statement about them
(a) P and Q are competitive neuromuscular blocking agents
(b) Q and R are competitive neuromuscular blocking agents
(c) R and S are non-competitive neuromuscular blocking agents
(d) P and S are competitive neuromuscular blocking agents
3. Which of the following skeletal muscle relaxants act directly on the contractile mechanism of the muscle fibers [GPAT-2011]
(a) Pancuronium
(b) Baclofen
(c) Dantrolene
(d) Chlorzoxazone
4. Skeletal muscle relaxation produced by the drug is effectively antagonized by Neostigmine [GATE-1990]
(a) Diazepam
(b) Succinylcholine
(c) Tubocurarine
(d) Aminophylline
5. Peripheral neurotransmitter is [GATE-1988]
(a) Histamine
(b) Noradrenaline
(c) Hydroxytryptamine
(d) Prostaglandin
6. Which of the following skeletal muscles is relaxed first by tubocurarine
(a) Respiratory
(b) Fingers
(c) Limbs
(d) Head and neck
7. Central muscle relaxants act by
(a) Decreasing nerve conduction
(b) Inhibiting spinal polysynaptic reflexes
(c) Blocking conduction across NM junction
(d) Causing CNS depression
8. Cisatracurium is preferred over atracurium, because
(a) It has rapid onset of action
(b) It causes less release of histamine
(c) It has short duration of action
(d) It has less depressant action on heart
9. Shortest acting competitive neuromuscular blocking agent is
(a) D-tubocurarine
(b) Pancuronium
(c) Mivacurium
(d) Pipecuronium
10. Which nondepolarizing agent is a ganglion blocker
(a) D-tubocurarine
(b) Gallamine
(c) Rocuronium
(d) Atracurium
ANSWER KEY
| 1-c | 2-d | 3-c | 4-b | 5-b | 6-b | 7-b | 8-b | 9-c | 10-a |
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