STERILIZATION GPAT MCQs Part – 8

TOP 10 MCQ

1. The time taken at a fixed temperature or the radiation dose required to achieve a 90% reduction in viable bacterial cells is called [GPAT – 2023 SHIFT – I]
(a) F value
(b) Z value
(c) D value
(d) T value

2. Pyrogens present in containers can be destroyed by heating the containers at [GPAT – 2020]
(a) 121°C for 15 mins
(b) 121°C for 30 mins
(c) 210°C for 4 h
(d) 210°C for 1 h

3. Containers may be rendered free from pyrogens by adequate cleaning and by [GPAT – 2019]
(a) Autoclaving at 121°C for 15 minutes
(b) Heating at 210°C for 3–4 hours
(c) Autoclaving at 121°C for 1 hour
(d) Heating at 100°C for 3–4 hours

4. The time in minutes at a specific temperature needed to kill a population of cell or spore is called [GPAT – 2013]
(a) D-value
(b) F-value
(c) Z-value
(d) None of these

5. HEPA filter prevents the entry of microbes of size [GPAT – 2013]
(a) Less than 0.3 µm
(b) Less than 0.1 µm
(c) More than 0.3 µm
(d) More than 0.1 µm

6. Browne’s tube is used [GPAT – 2013]
(a) As a chemical indicator for sterilization
(b) To check density
(c) To measure viscosity
(d) To store brown solutions

7. In relation to sterilization, what is the meaning of D_{300°F} = 2 minutes [GPAT – 2012]
(a) Death of all microorganisms in 2 minutes
(b) Death of 300 microorganisms in 2 minutes
(c) Death of all microorganisms in 2 minutes at 300°F
(d) Death of 90% microorganisms in 2 minutes at 300°F

8. By which mechanism are microorganisms killed by autoclaving [GPAT – 2012]
(a) Coagulation of the cellular proteins of the microorganisms
(b) Alkylation of essential cellular metabolites of microorganisms
(c) Stopping reproduction of microorganism cells as a result of lethal mutations
(d) Oxidation of RNA of microorganisms

9. HEPA filters are defined as A or more efficient in removing from the air B particles generated by vaporization of the hydrocarbon Emory 3004 [GPAT – 2011]
(a) A-99.99%, B-0.1 µm
(b) A-99.00%, B-0.3 µm
(c) A-99.99%, B-0.3 µm
(d) A-99.00%, B-0.1 µm

10. Class 100 area is referred to [GPAT – 2010]
(a) Manufacturing area
(b) Aseptic area
(c) Clean room
(d) Warehouse

ANSWER KEY