TABLET GPAT MCQs Part – 6

TOP 10 MCQ

1. Coating of Eudragit NE40D on tablets is done to prepare
(a) IR tablets
(b) Buccal tablets
(c) Sublingual tablets
(d) CR tablets

2. The rate-limiting step for the absorption of controlled release tablet is the
(a) Dissolution of the drug
(b) Metabolism of the drug
(c) Excretion of the drug
(d) Distribution of the drug

3. Nitrostat is an example of
(a) Bolus tablet
(b) Sublingual tablet
(c) Effervescent tablet
(d) CR tablet

4. Core tablet coated with cellulose acetate phthalate has been administered to a patient.Where do you expect the drug to be released?
(a) Intestine
(b) Liver
(c) Stomach
(d) Oral cavity

5. Which of the following are in-process QC test(s) for tablets
(a) Zeta-sizing test
(b) Hardness, friability, average weight
(c) Drug content, puncture test
(d) Dissolution test

6. Which of the following equipment measures weight variation using reflected energy
(a) Rotofsort
(b) Vericap-1200
(c) Rotofill
(d) Rotoweight

7. During compression of tablets, dwell time is [GPAT-2024]
(a) Time it takes for the punches to stop moving vertically and to achieve maximum penetration in the die under the primary
compression rollers
(b) Time it takes to compress the tablet
(c) Time it takes for the punches to eject the tablets
(d) Time it takes for the punches to eject tablet under the primary compression rollers

8. Match List I with List II [GPAT – 2023 SHIFT – III]
List I                                                               List II
DISSOLUTION TEST                  NAME
1. Type I                                          [P] Reciprocating holder
2. Type II                                        [Q] Rotating disk
3. USP App 6                                 [R] Basket type
4. USP App 7                                 [S] Cylinder apparatus
Choose the correct answer from the options below:
(a) 1-[R], 2-[Q], 3-[S], 4-[P]
(b) 1-[S], 2-[P], 3-[Q], 4-[R]
(c) 1-[Q], 2-[R], 3-[P], 4-[S]
(d) 1-[P], 2-[Q], 3-[R], 4-[S]

9. Noyes-Whitney equation predicts [GPAT – 2023 SHIFT – III]
(a) An increase of dissolution rate if the particle size is reduced by micronization because of an increase in area
(b) A relationship between the radius of the diffusing molecule and its diffusion coefficient
(c) The influence of electrolyte on the rate of dissolution
(d) An equilibrium between the surfactant and the drug molecules at the surface of the solution and in the bulk of the solution

10. Picking is a term used to describe [GPAT – 2023 SHIFT – III]
(a) Separation of tablet into two or more layers
(b) The situation when the surface material from a tablet that is sticking to and being removed from the tablet surface by punch
(c) Appearance of spots or discolouration on a tablet
(d) Partial or complete separation of the top and bottom crowns of a tablet from the main body of the tablet

ANSWER KEY