TETRACYLINE’S AND CHLOAMPHENICOL (BROAD-SPECTRUM ANTIBIOTICS)
TOP 10 MCQ
1. Which of the following drug is associated with the reaction of extreme photosensitivity [GPAT-2017]
(a) Niacin
(b) Digitalis
(c) Tetracycline
(d) Fluoroquinolones
2. Tetracyclines are avoided during pregnancy because [GATE-1997]
(a) It is teratogenic
(b) It may affect the bone growth of foetus
(c) It causes discoloration of mothers’ teeth
(d) It may cause abortion
3. Antibiotic which interacts with calcium ion is [GATE-1989]
(a) Erythromycin
(b) Streptomycin
(c) Tetracycline
(d) Ampicillin
4. Gray baby syndrome is due to the indiscriminate use of [GATE-1988]
(a) Streptomycin
(b) Chloramphenicol
(c) Penicillin
(d) Tetracycline
5. Tetracycline inhibits protein synthesis by
(a) Inhibiting initiation and causing misreading of mRNA
(b) Binding to 30S subunit and inhibiting binding of aminoacyl tRNA
(c) Inhibiting peptidyl transferase activity
(d) Inhibiting translocation
6. Which of the following Tetracycline can be used in renal failure without dose adjustment
(a) Oxytetracycline
(b) Doxycycline
(c) Demecycline
(d) Tetracycline
7. Fanconi’s syndrome is caused by
(a) Cephalosporins
(b) Chloramphenicol
(c) Decreased pseudo cholinesterase
(d) Old and degraded Tetracycline
8. Metabolism of chloramphenicol is by
(a) Glucuronide conjugation
(b) Oxidation
(c) Acetylation
(d) Sulfation
9. Which drug is primarily bacteriostatic
(a) Chloramphenicol
(b) Ceftriaxone
(c) Rifampicin
(d) Ciprofloxacin
10. Tetracyclines are ineffective against
(a) Chlamydia
(b) Brucella
(c) Trichomonas
(d) Rickettsia
ANSWER KEY
| 1-c | 2-b | 3-c | 4-b | 5-b | 6-b | 7-d | 8-a | 9-a | 10-c |
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