Object – To prepare and dispense 10gm Vanishing cream.
Reference – Gaud R.S. and Gupta G.D., Practical Pharmaceutics, CBS Publishers & Distributors Pvt. Ltd., 1st Edition 2002, Reprint 2019, Page no. 33.
Requirements –
- Chemicals – Stearic acid, Stearyl alcohol, Cetyl alcohol, Methyl paraben, Potassium hydroxide,
- Glassware – 1 Beaker, 1 Measuring cylinder, 1 China dish, Glass rod
Theory –
Vanishing cream is a particular type of skin cream used during the day time, either alone in which it is expected to immiscible or vanish on application, or in conjunction with powder when it must serve as a foundation for the makeup providing suitable adherent base for the powder.
These creams are water continuous cream with low or medium oil content. Most of the formulations contain high quantity of stearic acid as the oil phase. This provides an oil phase which melts above body temperature and crystallizes in a suitable form, so as to be immiscible and gives nongreasy film, and moreover can confirm a very attractive appearance to the product.
Formula Table:
| S. No. | Ingredients | Quantity Given | Quantity Taken |
| 1. | Stearic acid | 13.0 gm | 1.3 gm |
| 2. | Stearyl alcohol | 1.0 gm | 0.1 gm |
| 3. | Cetyl alcohol | 1.0 gm | 0.1 gm |
| 4. | Methyl paraben | 0.10 gm | 0.01 gm |
| 5. | Potassium hydroxide | 0.90 gm | 0.09 gm |
| 6. | Purified water | Upto 100 gm | Upto 10 gm |
Procedure
- Weight all the ingredients in the required quantity.
- Melt stearic acid, stearyl alcohol and cetyl alcohol at 75oC in a beaker (Part A).
- Dissolve potassium hydroxide in purified water at 75oC in another beaker and add methyl paraben (Part B).
- Add part A into part B at 75oC slowly with continuous stirring.
- Slowly stir the mixture until a smooth cream is formed at room temperature.
- Transfer in a suitable container and then label.
Category: Protective
Storage: Store in a well closed container in cool place.
Use: For external use only.
Result: 10gm vanishing cream had been prepared and dispensed.
