Object – To prepare and dispense 10ml Iodine Throat Paint.
Reference – Gaud R.S. and Gupta G.D., Practical Pharmaceutics, CBS Publishers & Distributors Pvt. Ltd., 1st Edition 2002, Reprint 2019, Page no. 294-295.
Requirements –
- Chemicals – Potassium iodide, Iodine, Ethanol (90%), Peppermint oil, Glycerin
- Glassware – 1 Beaker, 1 Measuring cylinder, 1 Mortar pestle
Theory –
Paints are liquid preparations intended for application to the mucous membrane or skin. They usually contain substances possessing analgesic, antiseptic, caustic or astringent properties. In this preparation Iodine acts as antiseptic, potassium iodide dissolves the iodine. Peppermint oil acts as flavouring agent and produce cooling effect. Alcohol is used as a solubilizing agent of the peppermint oil. This preparation contains iodine, hence should be prepared in glass apparatus. It should not be prepared in mortar and pestle because it contains the pores and iodine enters in these pores. It is difficult to washout the iodine and this entangled iodine can change the colour of the other preparation. The glycerine is used as vehicle in paints.
Formula Table:
| S. No. | Ingredients | Quantity Given | Quantity Taken |
| 1. | Potassium iodide | 2.5 gm | 0.25 gm |
| 2. | Iodine | 1.25 gm | 0.125 gm |
| 3. | Ethanol 90% | 4.0 ml | 0.4 ml |
| 4. | Peppermint oil | 0.4 ml | 0.04 ml |
| 5. | Purified water | 2.5 ml | 0.25 ml |
| 6. | Glycerin | Upto 100 ml | Upto 10 ml |
Procedure
- Weight all the ingredients in the required quantity.
- Dissolve potassium iodide and iodine in purified water in glass mortar and pestle.
- Add a small portion of glycerine.
- Add peppermint oil dissolve in ethanol and mix.
- Add sufficient glycerine to produce 10 ml.
- Transfer in a suitable container and then label.
Category: Antiseptic
Storage: Store in a air tight container in cool place.
Use: For internal use only.
Result: 10ml iodine throat paint had been prepared and dispensed.
