Object – To prepare and dispense 20ml Piperazine citrate Elixir I.P.
Reference – Mehta R. M., ‘Pharmaceutics-I’, Published by Vallabh Prakashan, 4th Edition 2007, Page No. 115.
Requirements –
- Chemicals – piperazine citrate, Glycerine, Chloroform spirit, Syrup, Peppermint oil and Distilled water
- Glassware – 1 Beaker,1 Measuring cylinder
Theory –
Elixirs are hydroalcoholic liquids that are clear, sweetened, aromatic, and intended for oral consumption. Ethyl alcohol (5–40%), water, glycerin or propylene glycol, flavouring, colouring, and an appropriate preservative are the major components of elixirs. The medicinal elixirs typically contain a strong medication, such as sedatives, antibiotics, or antihistamines. The flavoured elixirs are employed as flavours and carriers and contain no medication.
Formula Table:
| S. No. | Ingredients | Quantity Given | Quantity Taken |
| 1. | Piperazine citrate | 180gm | 3.6gm |
| 2. | Glycerine | 100ml | 2ml |
| 3. | Chloroform spirit | 5ml | 0.1ml |
| 4. | Simple syrup | 500ml | 10ml |
| 5. | Peppermint oil | 0.25ml | 0.005ml |
| 6. | Purified water | 1000ml | 20ml |
Procedure
- Dissolve piperazine citrate in sufficient purified water.
- Add peppermint oil, glycerin, chloroform spirit, simple syrup.
- Then add purified water to make up the required volume.
Category: Anthelmintic
Storage: Store in a well closed container.
Labelling – Make label in plane page (without lining).
Result: 20ml Piperazine citrate elixir I.P. had been prepared and dispensed.
