To prepare and dispense 20ml Piperazine citrate Elixir I.P.

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Object – To prepare and dispense 20ml Piperazine citrate Elixir I.P.

Reference – Mehta R. M., ‘Pharmaceutics-I’, Published by Vallabh Prakashan, 4th Edition 2007, Page No. 115.

Requirements –

  • Chemicals – piperazine citrate, Glycerine, Chloroform spirit, Syrup, Peppermint oil and Distilled water
  • Glassware – 1 Beaker,1 Measuring cylinder

Theory –

Elixirs are hydroalcoholic liquids that are clear, sweetened, aromatic, and intended for oral consumption. Ethyl alcohol (5–40%), water, glycerin or propylene glycol, flavouring, colouring, and an appropriate preservative are the major components of elixirs. The medicinal elixirs typically contain a strong medication, such as sedatives, antibiotics, or antihistamines. The flavoured elixirs are employed as flavours and carriers and contain no medication.

Formula Table:

S. No.IngredientsQuantity GivenQuantity Taken
1.Piperazine citrate180gm3.6gm
2.Glycerine100ml2ml
3.Chloroform spirit5ml0.1ml
4.Simple syrup500ml10ml
5.Peppermint oil0.25ml0.005ml
6.Purified water1000ml20ml

Procedure

  1. Dissolve piperazine citrate in sufficient purified water.
  2. Add peppermint oil, glycerin, chloroform spirit, simple syrup.
  3. Then add purified water to make up the required volume.

Category: Anthelmintic

Storage: Store in a well closed container.

Labelling – Make label in plane page (without lining).

Result: 20ml Piperazine citrate elixir I.P. had been prepared and dispensed.

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