To prepare and dispense 20ml Strong Iodine Solution I.P.

Object – To prepare and dispense 20ml Strong Iodine Solution I.P.

Requirements –

• Chemicals – Iodine, Potassium iodide, Alcohol and Distilled water
• Glassware – 1 Beaker, 1 Measuring cylinder, 1 Mortar pestle

Theory –

The iodine is very slightly soluble in water. Its solubility can be increased by potassium iodide. Potassium iodide reacts with iodine to form polyiodide, which is more soluble in 50% alcohol. As the preparation is used internally as well as externally, 90% alcohol is used as a vehicle. Alcohols absorb heat from the body and get evaporated, thereby causing a cooling effect.

Formula Table:

Calculation:

Iodine used for 20ml strong Iodine solution –  = 2gm

Potassium iodide used for 20ml strong Iodine solution –  = 1.2gm

90% alcohol used for 20ml strong Iodine solution – 90ml alcohol + 10ml water

Procedure

1. Triturate iodine and potassium iodide in mortar pestle.
2. The add 1/4^th quantity of 90% alcohol.
3. Transfer in a beaker and shake it well to dissolve.
4. Then add purified water to make up the required volume.
5. Transfer it to suitable container, label it and submit it.

Category: Antiseptic (Topically).

Storage: Store in a cool and dry place away from light.

Labelling: For external use only.

Result: 20ml Strong Iodine Solution I.P. had been prepared and dispensed.